Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC449H741N135O145S9

DescriptionStandard

        MKTLVLLSALALLAFQVQADPIQNRDEESKIDEQPGKEDQAVSVSFGDPEGSSLQEECDALRDRICYCRTSCKKRERLNGTCRKGHLMYKLCCR
    

Molecular Weight10639.09 Da

Isoelectric Point (pI)6.56

Net Charge (pH 7.0)-0.46

Net Charge (pH 7.4) -0.86

Charge Density (pH 7.0) -0.0049

GRAVY Index-0.58

Hydrophobic Moment 0.47

Boman Index-0.20

Instability Index44.05

Aliphatic Index 76.81

Aromaticity 0.0426

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4596.25

LogP -51.41

H-bond Donors 166.0

H-bond Acceptors 155.0

Rotatable Bonds 369.0

Heavy Atoms 738.0

Ring Count 8.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0112482 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence