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MYP_075265
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Basic Information
Unnamed
Antiviral
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C17H32N6O4
Standard
Sequence
LRP
Physicochemical Analysis
384.47 Da
9.75
0.76
0.56
0.2534
-0.77
0.96
-0.45
135.07
130.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
174.63
-0.82
6.0
5.0
10.0
27.0
1.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0194877 VERIFIED: YES
Provenance & Taxonomy
Zea mays [Plant]
ACE-inhibitory peptide
4577
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
0.27 μM
IC50
PaperStructures and activities of angiotensin converting enzyme inhibitors in ?-zein hydrolyzate PMID1368684 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1368684/
RECORD: Rec_0204605 VERIFIED: NO
Provenance & Taxonomy
Zea mays [Plant]
ACE-inhibitory peptide
4577
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive Antioxidant
Spontaneously hypertensive rat (SHR)
15 mmHg
SBP decrease
PaperVegetable foods: A cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities. PMID23598136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598136/
RECORD: Rec_0226882 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory ACE2 Activating Activator
ACE2
PaperWang Z., Fan H., Bao X., Wu J.. Angiotensin-converting enzyme 2 activation is not a common feature of angiotensin-converting enzyme inhibitory peptides. J. Agric. Food Chem., 71, 8867?8876, 2023.
RECORD: Rec_0259978 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
0.21 μM
IC50
PaperIntegration of QSAR modelling and QM/MM analysis to investigate functional food peptides with antihypertensive activity
RECORD: Rec_0279036 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
1 μM
IC50
PaperISOLATION AND CHARACTERIZATION OF PEPTIDES WITH ANTIHYPERTENSIVE ACTIVITY IN FOODSTUFFS. PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
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