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MYP_075254
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Basic Information
Sapecin B
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
34 amino acids
C169H285N53O47S6
Standard
Sequence
LTCEIDRSLCLLHCRLKGYLRAYCSQQKVCRCVQ
Physicochemical Analysis
4003.79 Da
8.92
3.79
3.44
0.1114
0.02
0.53
-0.14
36.53
100.29
0.0588
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1656.96
-16.06
66.0
58.0
136.0
275.0
3.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0043152 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. sanguis ST3t
3.8 μg/mL
IC50
PaperPurification, sequence and antibacterial activity of two novel sapecin homologues from Sarcophaga embryonic cells: similarity of sapecin B to charybdotoxin.
RECORD: Rec_0106880 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. bovis ATCC 27960t
0.9 μg/mL
IC50
PaperPurification, sequence and antibacterial activity of two novel sapecin homologues from Sarcophaga embryonic cells: similarity of sapecin B to charybdotoxin.
RECORD: Rec_0126294 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
PaperPubMed PMID: 7635204 | PubMed PMID: 8471044 PMID7635204;8471044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7635204/
RECORD: Rec_0129893 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus epidermidis IFO 3762
7.0 μg/mL
IC50
PaperPurification, sequence and antibacterial activity of two novel sapecin homologues from Sarcophaga embryonic cells: similarity of sapecin B to charybdotoxin.
RECORD: Rec_0134692 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus megaterium
PaperPubMed PMID: 7635204 | PubMed PMID: 8471044 PMID7635204;8471044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7635204/
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