Peptide Database

Peptide NameHNH endonuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length238 amino acids

Chemical FormulaC1192H1828N322O366S2

DescriptionStandard

        MVWNSEHNRYEFTPAHGADGPLITWTPERPEGSDLPSHTGSDIKSIDQATILVTPIPDGKDEYTTPPFPVPEERDLNDYILVFPADSGIKPIYVYLKDDPRDQAGTASGNGSQIKTGQKWLDLSVTNNGEGAKIPSNIADKLRGRHYDSFRKSREDLWLEISKDPELSKQFSNGNIEAMQEGKAPTAPFAGHYVGPKQVIKKFEIHHIKPIEEGGGVYDIDNLRITTPKLHKFIHYGE
    

Molecular Weight26589.33 Da

Isoelectric Point (pI)5.49

Net Charge (pH 7.0)-8.67

Net Charge (pH 7.4) -9.42

Charge Density (pH 7.0) -0.0364

GRAVY Index-0.74

Hydrophobic Moment 0.64

Boman Index-0.05

Instability Index44.53

Aliphatic Index 71.72

Aromaticity 0.0882

Extinction Coeff. Reduced 35410.00

Extinction Coeff. Oxidized 35410.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0170684 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella [Bacterium]

FamilyPyocin/Colicin

Tax ID590

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal

TargetEscherichia coli

RECORD: Rec_0330773 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Endonuclease Nuclease Non-hemolytic Non-ribosomal

TargetEscherichia coli