Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC358H572N96O96S8

DescriptionStandard

        MTQLLLLLVALLVLGRAPPGRSEFKRCWKGQGACRTYCTRQETYMHLCPDASLCCLSYALKPPPVPKPEYE
    

Molecular Weight8013.48 Da

Isoelectric Point (pI)8.85

Net Charge (pH 7.0)3.54

Net Charge (pH 7.4) 3.16

Charge Density (pH 7.0) 0.0498

GRAVY Index-0.09

Hydrophobic Moment 0.55

Boman Index0.03

Instability Index73.21

Aliphatic Index 85.21

Aromaticity 0.0845

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3026.35

LogP -23.60

H-bond Donors 110.0

H-bond Acceptors 109.0

Rotatable Bonds 252.0

Heavy Atoms 558.0

Ring Count 16.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0063326 VERIFIED: NO

Provenance & Taxonomy

OrganismCebus imitator [Animal]

FamilyDefensin

Tax ID9516

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0384728 VERIFIED: NO

Provenance & Taxonomy

OrganismSapajus apella (Brown-capped capuchin) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin