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MYP_075202
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Basic Information
A20L
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C142H236N36O34
Standard
Sequence
KWKSFLKTFKSAKKTVLHTLLKAISS
Physicochemical Analysis
2991.61 Da
10.78
6.84
6.58
0.2631
-0.14
0.65
-0.02
6.56
93.85
0.1154
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1159.04
-8.37
43.0
42.0
105.0
212.0
5.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0210017 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial
human erythrocytes
31.3 μg/mL
MHC
Paperhttps://pubmed.ncbi.nlm.nih.gov/17158938/ PMID17158938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17158938/
RECORD: Rec_0224586 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
six Gram-negative strains (geometric mean)
15.6 μg/mL
MIC
PMID17158938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17158938/
RECORD: Rec_0225344 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
PeptideV13K
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
MCF-7
5.1 μM
IC50
PaperStudies on mechanism of action of anticancer peptides by modulation of hydrophobicity within a defined structural framework PMID21252288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21252288/
RECORD: Rec_0234165 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa PAK
31.3 μg/mL
MIC
PMID17158938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17158938/
RECORD: Rec_0235452 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium tuberculosis H37Rv
83.7 μg/mL
MIC
PMID20858205 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20858205/
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