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MYP_075135
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Collagen boosting
Standard
3 amino acids
C16H27N3O4
Standard
Sequence
PPL
Physicochemical Analysis
325.40 Da
5.96
-0.04
-0.10
-0.0138
0.20
0.31
0.43
70.87
130.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
98.74
0.34
3.0
4.0
6.0
23.0
2.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0220460 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Tripeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Collagen boosting
Normal human fibroblasts (NHF) (In vitro)
ELISA; Immunofluorescence
PaperPatent US 10668000 B2 PatentUS 10668000 B2
RECORD: Rec_0232114 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
Dipeptidyl peptidase IV
390.14
IC50
PaperLafarga T., O¡¯Connor P., Hayes M.. Identification of novel dipeptidyl peptidase-IV and angiotensin-I-converting enzyme inhibitory peptides from meat proteins using in silico analysis. Peptides 59, 53-62, 2014.
RECORD: Rec_0256741 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
427.15
IC50
PaperWang Z., Zhang S., Jin H., Wang W., Huo J., Zhou L., Wang Y., Feng F., Zhang L.. Angiotensin-I-converting enzyme inhibitory peptides: Chemical feature based pharmacophore generation. Eur. J. Med. Chem., 46, 3428-3433, 2011.
RECORD: Rec_0377704 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Tripeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Collagen boosting
Human keratinocytes (In vitro)
ELISA; Immunofluorescence
PaperPatent US 10668000 B2 PatentUS 10668000 B2
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