Peptide Database

Peptide NameHcp1 family type VI secretion system effector

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length592 amino acids

Chemical FormulaC2995H4551N801O890S15

DescriptionStandard

        MSDLLYLKITGEKQGNISSGCGTYESVGNRWQVSHEDEIFVFSLANTVTSTGNGLNLQGLNFCKLIDKSTPLFCNTITQNERLYIEIDFYRINKTGRWERYYYIQLRNASVVNIHTSFTNNNLDTESITVTYEYIVCKHLIANTEFDYLAFPAEYNAMFIPRRVRPAQKTTPAPVPIVNPVPPPPEVTPVYAKSCLKEKGCTDAGTAEEPAENFGQMAIFAQPAVDDCCGYRHQSDDRSAIHPPVEGAAVPWVLASQVWGEWSLSGVLGATRGIPYIGALASALYIPSAGEGSARVPGRDEFWYEEELRQKALAGSTATTRVRFFWRDDIHGRPQVYGVHTGEGTPYENVRVANMLWNEETQRYEFTPAHGVDGPLITWTPEKPETGNLPGHTGNNRPPVDQPTILVTPIPDGKNEYTTPPFPLPDISDFNDYILVFPADSGIKPIYVYLKDDPRKQPGVVTGKGVELSPGTRWLDMSVTNQGNGAPIPAHIADKLRGREFKKFDDFREALWLEVSKDPVLMEQFCEDNQENLSNGYAPFSIKEGYYYGPKEIVKKFQIHHFIAIENGGGIYDIDNLRIVTPRLHDEIHYRR
    

Molecular Weight66498.98 Da

Isoelectric Point (pI)5.33

Net Charge (pH 7.0)-17.27

Net Charge (pH 7.4) -18.50

Charge Density (pH 7.0) -0.0292

GRAVY Index-0.44

Hydrophobic Moment 0.65

Boman Index0.02

Instability Index36.91

Aliphatic Index 76.08

Aromaticity 0.1098

Extinction Coeff. Reduced 103710.00

Extinction Coeff. Oxidized 104210.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0153875 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica subsp. salamae serovar 55:k:z39 str. 1315K [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli

RECORD: Rec_0327950 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyColicin/Bacteriocin

Tax ID28901

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence