Peptide Database

Peptide NameHNHc domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length940 amino acids

Chemical FormulaC4557H7120N1268O1357S21

DescriptionStandard

        MGEGHSNTTGHGARGPTGGVKGGSTGFGGGNPNSGKGWGVSQTPYGPLRNYNPSKFGSRSGGNRGGNNRSRHRGNPPSPPNLAQRPELQVAIVPGVAVPLSLVAGEWGFTLLKPKVVAAALDLALTRMAMFAVDAAPYAGRFAGVVGMLLAPSEIAKDDMSVIRRTVVTLPADKITTMPLAQLPTQPAVVADVRLHDVVQDGVQKIAVVKSKHVPITVPVVQAKPTDRTGVFTAQILNGMPPIHIHVDTSSSPPTAMQPSGISEVRDSPVTPVFSPLGSHSHDAIVYFPVETNTDPVYISVTTVLTPEQITQVEAENRQKQAQWDANYPVEAAEYQLSQANDALAQEQNNIVPYQAALDELKGTWEGRLLDDPDRYPFRDEIEEFISISSSSRYRFMFDIEIKNRQELENLLNIGGEAFDPFPDGMSPEEMEYYGYHAGLLMQALTIGHYDLLRKHLLAYQANINTAQLALDSIQHQLDMAINAVNNAEQHLTQVRGPLVETENARLTAEATKWQPRAEFEQWDANVTERWRIKDEQRAAEVAEWQQRVERERLAAEAADGFAKQQIAIRNNSFSLPAHPKGSTHTPGFAGVGMGTIALSSPVARGFSATLRTALARFSTIAPTLLARPIAMTVGSGFYPTKVGGGPDKPALVGSFPLSEMGLPPATPLPQQGEIDLPVRMLMKDQDDWTDVYAVKTGAANIAAKVKVATAQFDQSKGVYTFTTDSQPPRTFIFTPAKPPGMDISSVLPQPPSAPVVPPHTGADITFLATKPGLIFLALEEGDFHDYIIWFPAASGLEPVYIYFKTPRDEPGEVTGRGQQVAGVWLAEAGKGLGAPIPVQIADKLRGRKFSSFDRFREAFWQEVANDPELAAQFKPSNMDLMKNGYAPFVKKSDKSGKRVRIELHHKKPISQGGDVYHIDNINAVTPKRHIEIHSKNGGV
    

Molecular Weight102054.33 Da

Isoelectric Point (pI)6.25

Net Charge (pH 7.0)-7.36

Net Charge (pH 7.4) -8.96

Charge Density (pH 7.0) -0.0078

GRAVY Index-0.32

Hydrophobic Moment 0.71

Boman Index0.04

Instability Index44.09

Aliphatic Index 79.11

Aromaticity 0.0766

Extinction Coeff. Reduced 100270.00

Extinction Coeff. Oxidized 100270.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0045253 VERIFIED: NO

Provenance & Taxonomy

OrganismYersinia intermedia [Bacterium]

FamilyColicin pyosin nuclease

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence