Peptide Database

Peptide NameAlpha-1-proteinase inhibitor

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Standard StatusStandard

Sequence Length255 amino acids

Chemical FormulaC1314H2021N337O396S6

DescriptionStandard

        EDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLP
    

Molecular Weight29067.51 Da

Isoelectric Point (pI)5.11

Net Charge (pH 7.0)-12.34

Net Charge (pH 7.4) -13.06

Charge Density (pH 7.0) -0.0484

GRAVY Index-0.37

Hydrophobic Moment 0.78

Boman Index0.02

Instability Index27.61

Aliphatic Index 82.59

Aromaticity 0.1059

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18450.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0335096 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilySerpin

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protease inhibitor replacement