Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length458 amino acids

Chemical FormulaC2320H3686N632O640S9

DescriptionStandard

        TNPGCVVRITQAGLDYARQEGIAILEKELAQLKLPDISGDTRIKILGRAHYQISRLDLRNFHLPYSRISLVPNVGLQVSISNAFAKVSGNWRVKLRILRASGSFDLTLENIHIRINLRLGRNTSGRPTVDPSDCSTSISNVQLRFSGRFSWFYNLFRKSIASRIRKILESKVCDSAVTSVRRELQPYLQTLPVTARIDSVAGIDYSLVAPPTATAWSLDVSLKGEFFSLANRSSVPFFPPALGLPPDHDRMVYFGVSSYFFNTAGFTYQADGALVFEITDSMIPSDTDIRLSTSLFAAFIPQLEEMYPQLPMKLRLSTPFAPFLTIRPGGMLLQPVLDVQAYAILPNSSLAPLFLLSLTGNVSAVIDVRSGRIVGNLTVGRLFHSLKLFSFPLSAPQVWTLQSIMNFIASRVLLPRLNARLDEGFPLPLPARIQLSQILVQFHQNLLLLGANVRYQPR
    

Molecular Weight50960.52 Da

Isoelectric Point (pI)10.03

Net Charge (pH 7.0)15.92

Net Charge (pH 7.4) 15.32

Charge Density (pH 7.0) 0.0348

GRAVY Index0.14

Hydrophobic Moment 0.71

Boman Index0.10

Instability Index42.06

Aliphatic Index 107.51

Aromaticity 0.0939

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0165310 VERIFIED: NO

Provenance & Taxonomy

OrganismSyrrhaptes paradoxus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria