Peptide Database

Peptide NameAntimicrobial peptide UyCT1 (CT1) (Non-disulfide-bridged peptide 4.16) (NDBP-4.16) (Non-disulfide-bridged peptide 5.18) (NDBP-5.18) [Cleaved into: Antimicrobial peptide UyCT2 (Non-disulfide-bridged peptide 5.19) (NDBP-5.19)]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC396H617N99O115S5

DescriptionStandard

        MKTQLAFLAITVILMQLFAQTEAGFWGKLWEGVKNAIGKRGLRNVDQIADLFDSGLSDADDLFDSGLSDADAKFMKMFM
    

Molecular Weight8765.05 Da

Isoelectric Point (pI)4.58

Net Charge (pH 7.0)-3.49

Net Charge (pH 7.4) -3.72

Charge Density (pH 7.0) -0.0442

GRAVY Index0.15

Hydrophobic Moment 0.85

Boman Index0.15

Instability Index24.99

Aliphatic Index 91.52

Aromaticity 0.1139

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3455.07

LogP -27.44

H-bond Donors 118.0

H-bond Acceptors 117.0

Rotatable Bonds 300.0

Heavy Atoms 615.0

Ring Count 11.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0043159 VERIFIED: YES

Provenance & Taxonomy

OrganismUrodacus yaschenkoi [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetEscherichia coli

RECORD: Rec_0118343 VERIFIED: YES

Provenance & Taxonomy

OrganismUrodacus yaschenkoi [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetPseudomonas aeruginosa

RECORD: Rec_0310796 VERIFIED: YES

Provenance & Taxonomy

OrganismUrodacus yaschenkoi [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetStaphylococcus aureus