Peptide Database

Peptide Namealpha-III-gliadin (p62-p79; E76)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC70H100N14O19

DescriptionStandard

        PQLPYPQPELPY
    

Molecular Weight1441.63 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.04

Net Charge (pH 7.4) -1.10

Charge Density (pH 7.0) -0.0867

GRAVY Index-1.12

Hydrophobic Moment 0.15

Boman Index0.07

Instability Index114.18

Aliphatic Index 65.00

Aromaticity 0.1667

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 498.21

LogP -1.43

H-bond Donors 14.0

H-bond Acceptors 18.0

Rotatable Bonds 36.0

Heavy Atoms 103.0

Ring Count 7.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409347 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E76

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay