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MYP_074883
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Basic Information
Venom antimicrobial peptide-6
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C68H109N15O15
Standard
Sequence
IFGAIAGLLKNIF
Physicochemical Analysis
1376.68 Da
8.75
0.76
0.55
0.0584
1.70
0.46
0.66
29.97
165.38
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
481.63
-0.76
16.0
16.0
45.0
98.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0171014 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Beauveria spp
PMID19088182 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19088182/
RECORD: Rec_0173894 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
A. tumerfaciens
PMID19088182 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19088182/
RECORD: Rec_0183218 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Meucin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0208610 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
42.8 μM
MIC
PaperStructural and functional characterization of two genetically related meucin peptides highlights evolutionary divergence and convergence in antimicrobial peptides
RECORD: Rec_0216555 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Shewanella oneidensis
6.2 μM
MIC
PMID19088182 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19088182/
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