Peptide Database

Peptide NameVenom antimicrobial peptide-6

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC68H109N15O15

DescriptionStandard

        IFGAIAGLLKNIF
    

Molecular Weight1376.68 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0584

GRAVY Index1.70

Hydrophobic Moment 0.46

Boman Index0.66

Instability Index29.97

Aliphatic Index 165.38

Aromaticity 0.1538

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 481.63

LogP -0.76

H-bond Donors 16.0

H-bond Acceptors 16.0

Rotatable Bonds 45.0

Heavy Atoms 98.0

Ring Count 2.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0133389 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus eupeus [Animal]

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetBacillus sp. DM-1

RECORD: Rec_0136521 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial

TargetRabbit erythrocytes

Activity6.25 μM

MethodHemolysis

RECORD: Rec_0147395 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus eupeus [Animal]

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStenotrophomonus sp. YC-1

RECORD: Rec_0149079 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus eupeus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetBacillus sp

RECORD: Rec_0161396 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 30.8%, E 15.4%, T 30.8%, C 23.1% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antibacterial Toxic Antimicrobial Antifungal Hemolytic Anti-Gram-positive Cytotoxic Anti-Gram-negative

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