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MYP_074879
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Basic Information
α-MSH [4-10]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Regulatory peptide ▸ Biological regulation
Standard
7 amino acids
C44H59N13O10S
Standard
Sequence
MEHFRWG
Physicochemical Analysis
962.09 Da
6.50
-0.41
-0.68
-0.0585
-1.11
0.47
-0.08
50.00
0.00
0.2857
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
381.59
-1.25
14.0
12.0
29.0
68.0
4.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002734 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Melanocortin (α-MSH)
9606.0
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-HIV Anti-HSV
Herpesvirus, HIV
PaperAlpha-melanocyte-stimulating hormone peptides inhibit HIV-1 expression in chronically infected promonocytic U1 cells and in acutely infected monocytes; Patent: Treatment Of Ophthalmic Infections Using Antimicrobial Peptides PMID11073109 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11073109/ PatentUS 7244710
RECORD: Rec_0109346 VERIFIED: YES
Provenance & Taxonomy
Unknown [Animal]
ACTH4
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for ACTH4-10: PMID 10358199 PMID10358199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10358199/
RECORD: Rec_0149866 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Regulatory
PaperGao X. F., Wong T. C.. NMR studies of adrenocorticotropin hormone peptides in sodium dodecylsulfate and dodecylphosphocholine micelles: proline isomerism and interactions of the peptides with micelles. Biopolymers, 58, 20-32, 2001.
RECORD: Rec_0176496 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 6803044 B1 Evidence URLhttps://patents.google.com/patent/US6803044B1/en PatentUS 6803044 B1
RECORD: Rec_0240998 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperPatent US 7244710 B2 Evidence URLhttps://patents.google.com/patent/US7244710B2/en PatentUS 7244710 B2
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