Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length473 amino acids

Chemical FormulaC2339H3679N585O675S21

DescriptionStandard

        MLHFVIVALMALPHTCGHNPAIQVLLTNKGLQYGKHVGAEWIQDMLDHVTLPDIQGTFSTLFGTVSYTLSGITITKCDFPEPNVEYSQEYSGFKTSITGLSVALSGNWATKFGILHESGSFDMAIFGVDVTSVVKLKRKADGHLSVSSIICDGEVQDVDIRLYGGFSWIFQPFVHYIKGHIIEEIRKNICPAVQTSIEELETHLQAVNVSFDVNQVLSLELPLTGSPVVSPSNLTLGLKGEFYSLQTHAEPPFKSKPFMMPNIPGYMLSAGVSEFTLNSAAYGYFSAGKLQILITEKMVPKFSPIHLNTSSMGPYIPQLPKLFPGLPMTLQVYATEAPTFSLQSDVVNLTVQAAVKASAVESNGSSIPLFGLNVVVMLSGKMWIADGKVKGSVMLNNFTLTLASTQVGHFKTDSLENMCKKGIELFGVPQVNKKLAEGVMLPRMKRIQPVNSILTVEKGFIAISSDAQVLDTL
    

Molecular Weight51468.11 Da

Isoelectric Point (pI)6.23

Net Charge (pH 7.0)-4.38

Net Charge (pH 7.4) -5.43

Charge Density (pH 7.0) -0.0093

GRAVY Index0.20

Hydrophobic Moment 0.60

Boman Index0.20

Instability Index39.68

Aliphatic Index 98.65

Aromaticity 0.0867

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40130.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237344 VERIFIED: NO

Provenance & Taxonomy

OrganismOryzias latipes [Plant]

FamilyBPI

Tax ID8090

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence