Peptide Database

Peptide NameGlia-alpha2 (p60-p76; E66 and E73)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC99H138N20O27

DescriptionStandard

        QPFPQPELPYPQPELPY
    

Molecular Weight2040.27 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.24

Net Charge (pH 7.4) -2.45

Charge Density (pH 7.0) -0.1315

GRAVY Index-1.23

Hydrophobic Moment 0.16

Boman Index0.04

Instability Index139.08

Aliphatic Index 45.88

Aromaticity 0.1765

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 711.72

LogP -2.54

H-bond Donors 18.0

H-bond Acceptors 25.0

Rotatable Bonds 51.0

Heavy Atoms 146.0

Ring Count 10.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0118365 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E66; Reported substitutions/positions: E73

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay