Peptide Database

Peptide NameFGF-19

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length216 amino acids

Chemical FormulaC1069H1669N301O305S12

DescriptionStandard

        MRSGCVVVHVWILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFLRIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPMLPMVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK
    

Molecular Weight24002.30 Da

Isoelectric Point (pI)6.55

Net Charge (pH 7.0)-1.64

Net Charge (pH 7.4) -2.49

Charge Density (pH 7.0) -0.0076

GRAVY Index-0.15

Hydrophobic Moment 0.50

Boman Index0.04

Instability Index54.72

Aliphatic Index 87.55

Aromaticity 0.0833

Extinction Coeff. Reduced 26930.00

Extinction Coeff. Oxidized 27180.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0393203 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsAmino acids 1-24 form the signal peptide of the precursor protein.

Bio-Activity Profile

Function

Receptor agonist Immunomodulatory Signaling peptide

Targetfibroblast growth factor receptor 4 (Human)

Activity1 nM

MethodKd