Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC160H244N46O49S6

DescriptionStandard

        DHYICARNGGTCHYSSCPLFTKIEGTCYGGKAKCC
    

Molecular Weight3788.32 Da

Isoelectric Point (pI)8.31

Net Charge (pH 7.0)1.87

Net Charge (pH 7.4) 1.47

Charge Density (pH 7.0) 0.0535

GRAVY Index-0.29

Hydrophobic Moment 0.30

Boman Index0.02

Instability Index71.17

Aliphatic Index 39.14

Aromaticity 0.1143

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1520.78

LogP -18.69

H-bond Donors 60.0

H-bond Acceptors 59.0

Rotatable Bonds 120.0

Heavy Atoms 261.0

Ring Count 7.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0335136 VERIFIED: YES

Provenance & Taxonomy

OrganismCeratotherium simum [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)