Peptide Database

Peptide NameVenom antimicrobial peptide-6 (MeAMP-like toxin) (Meucin-13) (Non-disulfide bridged protein family 5) (NDBP-5) (Non-disulfide-bridged peptide 4.6) (NDBP-4.6) (VAMP-2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC370H589N87O100S4

DescriptionStandard

        MKSQTFFLLFLVVFLLAITQSEAIFGAIAGLLKNIFGKRSLRDMDTMKYLYDPSLSAADLKTLQKLMENY
    

Molecular Weight7984.42 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)1.50

Net Charge (pH 7.4) 1.27

Charge Density (pH 7.0) 0.0214

GRAVY Index0.38

Hydrophobic Moment 0.66

Boman Index0.18

Instability Index43.65

Aliphatic Index 111.57

Aromaticity 0.1286

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3024.36

LogP -19.26

H-bond Donors 105.0

H-bond Acceptors 106.0

Rotatable Bonds 272.0

Heavy Atoms 561.0

Ring Count 10.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0378465 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus eupeus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Hemolytic

TargetGram-negative and Gram-positive bacteria