Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC225H368N58O69S3

DescriptionStandard

        MAKQQKNLVEIEVMNSLQELTLEELDNVLGACSVIIHFIQTKQW
    

Molecular Weight5085.87 Da

Isoelectric Point (pI)4.70

Net Charge (pH 7.0)-3.41

Net Charge (pH 7.4) -3.70

Charge Density (pH 7.0) -0.0775

GRAVY Index0.05

Hydrophobic Moment 0.42

Boman Index0.11

Instability Index69.76

Aliphatic Index 119.55

Aromaticity 0.0455

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2086.59

LogP -16.75

H-bond Donors 69.0

H-bond Acceptors 70.0

Rotatable Bonds 178.0

Heavy Atoms 355.0

Ring Count 4.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057229 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus mitis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria