Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC368H608N110O99S8

DescriptionStandard

        MRILVLLVAISLFLYQDTPVRSELERDRICGYGTARCRRKCKIQEHRIGRCPNTYPCCLKPWDVSSLNIKLC
    

Molecular Weight8413.96 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)6.52

Net Charge (pH 7.4) 6.14

Charge Density (pH 7.0) 0.0906

GRAVY Index-0.11

Hydrophobic Moment 0.58

Boman Index-0.10

Instability Index35.98

Aliphatic Index 100.14

Aromaticity 0.0694

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3398.37

LogP -29.57

H-bond Donors 129.0

H-bond Acceptors 115.0

Rotatable Bonds 279.0

Heavy Atoms 585.0

Ring Count 11.0

Amide Bonds 75.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0223835 VERIFIED: NO

Provenance & Taxonomy

OrganismSciurus vulgaris [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence