Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC399H617N109O104S11

DescriptionStandard

        MTLTRKMSYIVFAFFFIFAQFPSGCQAGLEYSKPLPGGDFAACEPCRLGRGKCRKMCTEDEKPVGHCKLNFFCCRRKVS
    

Molecular Weight8957.55 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)6.51

Net Charge (pH 7.4) 6.11

Charge Density (pH 7.0) 0.0824

GRAVY Index-0.09

Hydrophobic Moment 0.59

Boman Index-0.00

Instability Index44.81

Aliphatic Index 51.90

Aromaticity 0.1392

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3406.53

LogP -30.29

H-bond Donors 127.0

H-bond Acceptors 123.0

Rotatable Bonds 293.0

Heavy Atoms 623.0

Ring Count 17.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0204545 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera leo [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0336175 VERIFIED: NO