Peptide Database

Peptide NameUnnamed

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC42H54N8O9

DescriptionStandard

        YPFGFKG
    

Molecular Weight814.93 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.1083

GRAVY Index-0.29

Hydrophobic Moment 0.25

Boman Index0.32

Instability Index20.11

Aliphatic Index 0.00

Aromaticity 0.4286

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 275.38

LogP -0.36

H-bond Donors 9.0

H-bond Acceptors 10.0

Rotatable Bonds 22.0

Heavy Atoms 59.0

Ring Count 4.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0204627 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Opioid

Targetmu opioid receptor

Activity0.02 μM

MethodIC50

PaperDooley C.T., Kaplan R.A., Chung N.N., Schiller P.W., Bidlack J.M., Houghten R.A.. Six highly active mu-selective opioid peptides identified from two synthetic combinatorial libraries. Peptide Research, 8, 3, 124-137(1995). PMID7670227 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7670227/

RECORD: Rec_0268310 VERIFIED: NO