Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC922H1395N207O280S7

DescriptionStandard

        IDDLAEVDYSLNSLPAVFQPFIDLDLKGIVYPAGNYAGPPYVAAPFTIPDQSDSMLHLAFSEYFFQTSSFAYYTAGAFSITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLTATEIPIISLEQDSFTVEIRGSMEVFAVLPDSATESLFTMNIAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight20083.61 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-15.14

Net Charge (pH 7.4) -15.47

Charge Density (pH 7.0) -0.0828

GRAVY Index0.34

Hydrophobic Moment 0.55

Boman Index0.26

Instability Index44.02

Aliphatic Index 96.01

Aromaticity 0.1311

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7660.64

LogP -79.67

H-bond Donors 260.0

H-bond Acceptors 273.0

Rotatable Bonds 634.0

Heavy Atoms 1416.0

Ring Count 37.0

Amide Bonds 194.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0367392 VERIFIED: NO

Provenance & Taxonomy

OrganismSpizaetus tyrannus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria