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MYP_074648
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C129H208N36O31
Standard
Sequence
GWKSVFRKAKKVGKTVGGLALDHYL
Physicochemical Analysis
2759.25 Da
10.30
4.84
4.58
0.1937
-0.22
0.79
0.01
23.46
89.60
0.1200
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1096.18
-7.66
40.0
37.0
94.0
196.0
5.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0081776 VERIFIED: YES
Provenance & Taxonomy
Hippoglossoides platessoides [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
A. salmonicida 97-4
8 μg/mL
MIC
PaperPatenting computer-designed peptides. Journal of Computer-Aided Molecular Design, 12: 543-556 Evidence URLhttps://camp3.bicnirrh.res.in/seqDisp.php?id=CAMPSQ2883
RECORD: Rec_0083718 VERIFIED: YES
Provenance & Taxonomy
American plaice [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C-terminal NH2
Bio-Activity Profile
Antimicrobial Antifungal
S. enterica serovar Typhimurium 14028s
32 μM
MIC
PaperNovel antimicrobial peptides derived from flatfish genes PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
RECORD: Rec_0133087 VERIFIED: YES
Provenance & Taxonomy
Hippoglossoides platessoides [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli CGSC4908
4 μg/mL
MIC
PaperPatenting computer-designed peptides. Journal of Computer-Aided Molecular Design, 12: 543-556 Evidence URLhttps://camp3.bicnirrh.res.in/seqDisp.php?id=CAMPSQ2883
RECORD: Rec_0148312 VERIFIED: YES
Provenance & Taxonomy
Hippoglossoides platessoides [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis C621
64 μg/mL
MIC
PaperPatenting computer-designed peptides. Journal of Computer-Aided Molecular Design, 12: 543-556 Evidence URLhttps://camp3.bicnirrh.res.in/seqDisp.php?id=CAMPSQ2883
RECORD: Rec_0171817 VERIFIED: YES
Provenance & Taxonomy
Hippoglossoides platessoides [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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