Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC541H874N148O166S3

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTTDMNWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNTGPTSISLTSCRTTSGDIDIKLNGKT
    

Molecular Weight12203.81 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)3.21

Net Charge (pH 7.4) 2.97

Charge Density (pH 7.0) 0.0282

GRAVY Index-0.01

Hydrophobic Moment 0.54

Boman Index0.11

Instability Index19.33

Aliphatic Index 93.16

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5016.30

LogP -58.19

H-bond Donors 179.0

H-bond Acceptors 175.0

Rotatable Bonds 402.0

Heavy Atoms 858.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0404588 VERIFIED: NO

Provenance & Taxonomy

OrganismRhadina sibilatrix [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria