Peptide Database

Peptide NameMussel defensin MGD-2

Function Ontology

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Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC122H175N39O37S3

DescriptionStandard

        GFFGGNDEPCHQHCKSIRGYRGGYCS
    

Molecular Weight2876.13 Da

Isoelectric Point (pI)7.96

Net Charge (pH 7.0)0.91

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0348

GRAVY Index-0.92

Hydrophobic Moment 0.49

Boman Index-0.11

Instability Index13.32

Aliphatic Index 15.00

Aromaticity 0.1538

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1230.91

LogP -15.92

H-bond Donors 46.0

H-bond Acceptors 43.0

Rotatable Bonds 91.0

Heavy Atoms 201.0

Ring Count 7.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0210816 VERIFIED: YES

Provenance & Taxonomy

OrganismHistoplasma capsulatum [Fungus]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)