Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC392H602N102O114S10

DescriptionStandard

        MKTFSVAVVVAVLLAFVYLQESSAFPPSKVPVIDDAAAAAYEEISDDSWKTPYTNRHKRSPAGCRFCCGCCPGMVGCGVCCNF
    

Molecular Weight8888.24 Da

Isoelectric Point (pI)6.51

Net Charge (pH 7.0)-0.49

Net Charge (pH 7.4) -0.89

Charge Density (pH 7.0) -0.0059

GRAVY Index0.32

Hydrophobic Moment 0.40

Boman Index0.16

Instability Index58.25

Aliphatic Index 70.48

Aromaticity 0.1084

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3384.39

LogP -34.07

H-bond Donors 124.0

H-bond Acceptors 125.0

Rotatable Bonds 275.0

Heavy Atoms 618.0

Ring Count 17.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0033222 VERIFIED: NO

Provenance & Taxonomy

OrganismTetraodon nigroviridis [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence