Peptide Database

Peptide NameLTP2(lipid transfer protein) alpha-1 isoform

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC293H465N89O93S8

DescriptionStandard

        ACQASQLAVCASAILSGAKPSGECCGNLRAQQGCFCQYAKDPTYGQYIRSPHARDTLTSCGLAVPHC
    

Molecular Weight6978.89 Da

Isoelectric Point (pI)8.21

Net Charge (pH 7.0)1.89

Net Charge (pH 7.4) 1.47

Charge Density (pH 7.0) 0.0282

GRAVY Index-0.08

Hydrophobic Moment 0.38

Boman Index0.05

Instability Index48.93

Aliphatic Index 64.33

Aromaticity 0.0597

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2900.15

LogP -39.07

H-bond Donors 107.0

H-bond Acceptors 105.0

Rotatable Bonds 221.0

Heavy Atoms 483.0

Ring Count 10.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0316677 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyLTP2 alpha-

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Antileishmanial

TargetLeishmania donovani MHOM/SD/00/1S-2D (promastigote)

Activity>100 μM

MethodLC50; MTT assay