Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length410 amino acids

Chemical FormulaC2084H3227N533O596S15

DescriptionStandard

        PQQGHFTLRSLFFSQGEVFVLARHPFFPGQISRILFPRMLLSVMSLLFIAEGFSVIRSPSNPSDVQVNIPLSVFCRLRINAVDFPETSASFIPGTGVSLSVAHASATISADWRMNTWLLKDQGGITVSISGLFIAVIFKVSRDSTGRLSILLHNCQLSINSLKLFFMLGRILSVQPLLMHSDRYKYLHLEILDNDSLQGTVYPVGSHTEPPFVPAPFDFPNQGDSMLYLGVSSYFIKSASLAYYRAGVFNIAISKEVSIIFNFFSSEIPQIALSYVTACPVLLKLMATSPPAVSLNADRCILQITGCVEVFAVLPNSTTQYIFRGNLTLCFQTQKQLHLCLYLRQYLSVYTVTEDCSVFFPADSQYQRQFDNNQTEVDYLITSEEVTKGNSESNVNDLNIRTEQNFIVSA
    

Molecular Weight45765.10 Da

Isoelectric Point (pI)6.27

Net Charge (pH 7.0)-2.39

Net Charge (pH 7.4) -3.04

Charge Density (pH 7.0) -0.0058

GRAVY Index0.24

Hydrophobic Moment 0.60

Boman Index0.17

Instability Index42.33

Aliphatic Index 101.00

Aromaticity 0.1146

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 32360.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0291912 VERIFIED: NO

Provenance & Taxonomy

OrganismButeo japonicus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria