‹ ›
MYP_074552
← PREVIOUS NEXT → BACK
Basic Information
Kappa-buthitoxin-Tt2b
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Membrane / Ion-channel modulation ▸ Ion channel inhibition
Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
28 amino acids
C128H210N42O39S7
Standard
Sequence
GCMPEYCAGQCRGKVSQDYCLKNCRCIR
Physicochemical Analysis
3185.75 Da
8.66
2.70
2.40
0.0964
-0.49
0.51
-0.22
47.97
41.79
0.0714
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1342.53
-16.33
53.0
49.0
106.0
216.0
3.0
30.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0395857 VERIFIED: YES
Provenance & Taxonomy
Tityus trivittatus [Animal]
Potassium channel inhibitor family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
2-24; 7-20; 11-26
Bio-Activity Profile
Toxin Venom Potassium channel inhibitor family
PaperPDB 2LI3 structural record; NMR; chain A; residues 1-28
RECORD: Rec_0411182 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic
PaperIn silico approach for predicting toxicity of peptides and proteins PMID24058508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24058508/