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MYP_074534
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Basic Information
Neutrophil defensin 2 (RMAD-2; primates, mammals, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
30 amino acids
C152H225N43O37S7
Standard
Sequence
ACYCRIPACLAGERRYGTCFYMGRVWAFCC
Physicochemical Analysis
3471.13 Da
8.68
2.74
2.45
0.0912
0.41
0.36
0.10
79.75
49.00
0.2000
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1280.04
-9.63
54.0
47.0
104.0
239.0
8.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005045 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Cryptococcus neoformans
PaperPubMed PMID: 10531277 PMID10531277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10531277/
RECORD: Rec_0017507 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus and Listeria monocytogenes
PaperPubMed PMID: 10531277 PMID10531277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10531277/
RECORD: Rec_0033047 VERIFIED: NO
Provenance & Taxonomy
Macaca mulatta [Animal]
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperPatent US 2008/0269122 A1 Evidence URLhttps://patents.google.com/patent/US20080269122A1/en PatentUS 2008/0269122 A1
RECORD: Rec_0052014 VERIFIED: NO
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
2-29; 4-19; 9-30
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0095057 VERIFIED: YES
Provenance & Taxonomy
Rhesus macaque [Animal]; Mammalia [Animal]
Defensin
33208; 40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
2-19; 4-29; 9-30
Paclitaxel conjugation
Bio-Activity Profile
Antimicrobial
PMID8890190 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8890190/
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