Peptide Database

Peptide NameP3

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC87H169N41O17

DescriptionStandard

        RRRQKRIVVRRRLIR
    

Molecular Weight2061.54 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.76

Net Charge (pH 7.4) 8.55

Charge Density (pH 7.0) 0.5839

GRAVY Index-1.48

Hydrophobic Moment 0.38

Boman Index-1.11

Instability Index190.99

Aliphatic Index 116.67

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1035.03

LogP -9.86

H-bond Donors 42.0

H-bond Acceptors 26.0

Rotatable Bonds 76.0

Heavy Atoms 145.0

Ring Count 0.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0157146 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus 1199B

Activity50 μM

MethodMIC

RECORD: Rec_0227860 VERIFIED: NO

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAhx, 6-aminohexamoic acid

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

RECORD: Rec_0318840 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity50 μM

MethodHemolysis

RECORD: Rec_0363113 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus 1199

Activity50 μM

MethodMIC

RECORD: Rec_0397299 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorescein/FITC labeling

C-TermNone

Other ModsLinker 6-aminohexamoic acid (Ahx)

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery