Peptide Database

Peptide NameSLAY-screened peptide P1481

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC112H167N29O27S2

DescriptionStandard

        RRHPSVLYPCTFQIVYYGLC
    

Molecular Weight2415.83 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)1.82

Net Charge (pH 7.4) 1.54

Charge Density (pH 7.0) 0.0912

GRAVY Index0.18

Hydrophobic Moment 0.38

Boman Index0.12

Instability Index74.74

Aliphatic Index 87.50

Aromaticity 0.2000

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 895.36

LogP -5.22

H-bond Donors 34.0

H-bond Acceptors 32.0

Rotatable Bonds 70.0

Heavy Atoms 170.0

Ring Count 7.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401052 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/