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MYP_074484
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Basic Information
TL-4 (Derived from Temporin-4Tl (TL))
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C92H136N20O15
Standard
Sequence
FVKWWSKWLKKIL
Physicochemical Analysis
1762.19 Da
10.48
3.76
3.55
0.2889
0.00
0.77
0.16
18.26
112.31
0.3077
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
584.20
2.93
22.0
19.0
57.0
127.0
7.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0245059 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
macrophages cells induced by TL-4 is 116
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
RECORD: Rec_0248818 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (KCTC 1621)
2 μM
MIC
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
RECORD: Rec_0282353 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
RECORD: Rec_0378952 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
RECORD: Rec_0401072 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
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