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MYP_074484
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Basic Information
TL-4 (Derived from Temporin-4Tl (TL))
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C92H136N20O15
Standard
Sequence
FVKWWSKWLKKIL
Physicochemical Analysis
1762.19 Da
10.48
3.76
3.55
0.2889
0.00
0.77
0.16
18.26
112.31
0.3077
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
584.20
2.93
22.0
19.0
57.0
127.0
7.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029713 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-positive bacteria: Bacillus subtilis (KCTC 3068)
4 μM
MIC
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
RECORD: Rec_0117231 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-negative bacteria: Escherichia coli (KCTC 1682)
8 μM
MIC
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
RECORD: Rec_0140752 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium (KCTC 1926)
2 μM
MIC
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
RECORD: Rec_0190156 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa (KCTC 1637)
16 μM
MIC
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
RECORD: Rec_0217677 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis (KCTC 1917)
8 μM
MIC
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
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