Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length286 amino acids

Chemical FormulaC1437H2258N350O399S12

DescriptionStandard

        MGNICQVVAKSVSSKLEPFFQTMPVTAKIDKVAGIDYSLLAPPIATTETLDGQLKGEFFSLAHRSPPPFAPPALALPMDHDHMVYLGISDYFFNTAGLVYQQAGALNLTLKDDMIPKKSKFHLTTKYFGTLIPKLAKMFPNMSMQFLIRVSSPPHLTVSPAGLACTPTLEAQAFAVLPNSSLAPLFLLGMSTNASVEVGAVSDRLVGELSLDKLLLELKHSDIGPFSVELLQAVMNYIVPTTVLPKVNERLQKGYPLPLPADVQLFNLVLQSYQNFLLFGADVLYH
    

Molecular Weight31206.19 Da

Isoelectric Point (pI)6.37

Net Charge (pH 7.0)-1.89

Net Charge (pH 7.4) -2.55

Charge Density (pH 7.0) -0.0066

GRAVY Index0.27

Hydrophobic Moment 0.64

Boman Index0.21

Instability Index38.25

Aliphatic Index 104.34

Aromaticity 0.0909

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0265366 VERIFIED: NO

Provenance & Taxonomy

OrganismPipistrellus kuhlii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria