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MYP_074438
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Basic Information
Brevinin-1V
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
24 amino acids
C124H209N29O28S2
Standard
Sequence
FLPLIASVAANLVPKIFCKITKKC
Physicochemical Analysis
2618.29 Da
9.70
3.74
3.50
0.1557
1.06
0.69
0.31
18.56
134.17
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
902.67
-3.68
32.0
34.0
85.0
183.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006792 VERIFIED: YES
Provenance & Taxonomy
Odorrana versabilis [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
18-24
Bio-Activity Profile
Antimicrobial Antibacterial
PaperY.J. Basir et al. / Biochimica et Biophysica Acta 1543 (2000) 95-105. Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris PMID11087945 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087945/
RECORD: Rec_0033155 VERIFIED: YES
Provenance & Taxonomy
Hainan odorous [Animal]
Brevinin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial
PMID22450466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22450466/
RECORD: Rec_0046474 VERIFIED: YES
Provenance & Taxonomy
Odorrana versabilis [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Psychrobacter faecalis X29
9.5 μM
MIC
PMID16139929;22450466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16139929/
RECORD: Rec_0073993 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Rhodococcus rhodochrous X15
9.5 μM
MIC
PaperNovel antimicrobial peptides isolated from the skin secretions of Hainan odorous frog, Odorrana hainanensis.
RECORD: Rec_0097081 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
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