Peptide Database

Peptide NameDefensin-7

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC449H720N130O139S7

DescriptionStandard

        MRTLTLISAILLVTLQAQADPLPDTSDEVQVQEQAAAENPDVAISFAGDENSAFQVSDLVRGIRCRCTRGFCLFPERNSGFCLLRGIRYSFCCR
    

Molecular Weight10387.76 Da

Isoelectric Point (pI)4.92

Net Charge (pH 7.0)-2.54

Net Charge (pH 7.4) -2.86

Charge Density (pH 7.0) -0.0270

GRAVY Index0.07

Hydrophobic Moment 0.65

Boman Index0.01

Instability Index23.34

Aliphatic Index 90.32

Aromaticity 0.0745

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4352.66

LogP -48.18

H-bond Donors 157.0

H-bond Acceptors 144.0

Rotatable Bonds 341.0

Heavy Atoms 725.0

Ring Count 11.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0367395 VERIFIED: NO

Provenance & Taxonomy

OrganismTupaia chinensis [Animal]

FamilyDefensin

Tax ID246437

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal