Peptide Database

Peptide NameMagainin-2 [L6I][A15L]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC117H186N30O29S

DescriptionStandard

        GIGKFIHSAKKFGKLFVGEIMNS
    

Molecular Weight2508.98 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.59

Charge Density (pH 7.0) 0.1237

GRAVY Index0.20

Hydrophobic Moment 0.70

Boman Index0.21

Instability Index1.57

Aliphatic Index 84.78

Aromaticity 0.1304

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 957.13

LogP -6.86

H-bond Donors 33.0

H-bond Acceptors 34.0

Rotatable Bonds 88.0

Heavy Atoms 177.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0378706 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Hemolytic Antimicrobial Antibacterial

TargetHuman erythrocytes

Activity260 μM

MethodEC50

RECORD: Rec_0409946 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-Gram-negative Antimicrobial Antibacterial

TargetPseudomonas aeruginosa

Activity76 μM

MethodMIC

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