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MYP_074410
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Basic Information
Magainin-2 [L6I][A15L]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
23 amino acids
C117H186N30O29S
Standard
Sequence
GIGKFIHSAKKFGKLFVGEIMNS
Physicochemical Analysis
2508.98 Da
10.00
2.85
2.59
0.1237
0.20
0.70
0.21
1.57
84.78
0.1304
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
957.13
-6.86
33.0
34.0
88.0
177.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0077231 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
38 μM
MIC
PMID9042968;9166783 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9042968/
RECORD: Rec_0102992 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 17.4%, T 43.5%, C 39.1% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0203768 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli
19-38 μM
MIC
PMID9042968;9166783 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9042968/
RECORD: Rec_0262176 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
150 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/9166783/ PMID9166783 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9166783/
RECORD: Rec_0282970 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
260 μM
Hemolysis
PMID9042968;9166783 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9042968/
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