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MYP_074387
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Basic Information
Antimicrobial peptide Thaulin-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
26 amino acids
C114H204N34O30
Standard
Sequence
NGNLLGGLLRPVLGVVKGLTGGLGKK
Physicochemical Analysis
2531.05 Da
11.26
3.76
3.55
0.1445
0.40
0.61
0.23
21.38
138.46
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1028.40
-9.85
35.0
34.0
88.0
178.0
1.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0271003 VERIFIED: YES
Provenance & Taxonomy
skin,a Patagonian frog,Pleurodema thaul,South America [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
62.5 μg/mL
MIC
PMID28025119 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28025119/
RECORD: Rec_0359636 VERIFIED: YES
Provenance & Taxonomy
Pleurodema thaul [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
500 μg/mL
MIC
PMID28025119 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28025119/
RECORD: Rec_0374189 VERIFIED: YES
Provenance & Taxonomy
Pleurodema thaul [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Klebsiella pneumoniae
125 μg/mL
MIC
PaperThaulin-1: The first antimicrobial peptide isolated from the skin of a Patagonian frog Pleurodema thaul (Anura: Leptodactylidae: Leiuperinae) with activity against Escherichia coli.
RECORD: Rec_0375571 VERIFIED: YES
Provenance & Taxonomy
Pleurodema thaul [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922
62.5 μg/mL
MIC
PaperThaulin-1: The first antimicrobial peptide isolated from the skin of a Patagonian frog Pleurodema thaul (Anura: Leptodactylidae: Leiuperinae) with activity against Escherichia coli.
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