Peptide Database

Peptide NameDermaseptin

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC380H622N102O123S3

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSICEEEKRENEEKENQEDDEQSEEKRALWKDLLKNVGKAAGKAVLNKVTDMVNQGEQ
    

Molecular Weight8683.81 Da

Isoelectric Point (pI)4.85

Net Charge (pH 7.0)-4.48

Net Charge (pH 7.4) -4.75

Charge Density (pH 7.0) -0.0590

GRAVY Index-0.61

Hydrophobic Moment 0.71

Boman Index-0.13

Instability Index51.12

Aliphatic Index 91.05

Aromaticity 0.0526

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3731.37

LogP -34.36

H-bond Donors 125.0

H-bond Acceptors 122.0

Rotatable Bonds 315.0

Heavy Atoms 608.0

Ring Count 5.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0236082 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa camba [Bacterium]

FamilyFrog skin active peptide (FSAP) family; Dermaseptin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Amphibian defense peptide Non-hemolytic Non-ribosomal