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MYP_074332
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Basic Information
Myticin-A
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
40 amino acids
C187H283N59O50S9
Standard
Sequence
HSHACTSYWCGKFCGTASCTHYLCRVLHPGKMCACVHCSR
Physicochemical Analysis
4446.20 Da
8.74
4.11
3.53
0.1028
0.04
0.52
0.06
68.56
41.50
0.1000
8480.00
8980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1706.53
-20.05
71.0
68.0
136.0
305.0
11.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0278013 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus luteus
2.25-4.5 μM
MBC
PaperPubMed PMID: 10491159 PMID10491159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10491159/
RECORD: Rec_0285817 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
29158
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
P-aeruginosa
>20 μM
MIC
PaperMyticin, a novel cysteine-rich antimicrobial peptide isolated from haemocytes and plasma of the mussel Mytilus galloprovincialis
RECORD: Rec_0286334 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Myticin
29158
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
20 μM
MIC
PMID10491159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10491159/
RECORD: Rec_0295711 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0302983 VERIFIED: NO
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
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