Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length231 amino acids

Chemical FormulaC1160H1780N268O346S9

DescriptionStandard

        PMPIDDLVEVDYSLNGLPAVFQQFIDLDLKGIVYPAGNHTGSTCVAVPFTIPDQSDSMLHLAFSEDFFQTASFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLEQDSFTVEIPGSMEVFAVLPDSTTQLLFTMNIAANTSIALNIFDQKLVGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSRGFPLP
    

Molecular Weight25304.71 Da

Isoelectric Point (pI)4.13

Net Charge (pH 7.0)-16.77

Net Charge (pH 7.4) -17.08

Charge Density (pH 7.0) -0.0726

GRAVY Index0.41

Hydrophobic Moment 0.55

Boman Index0.27

Instability Index44.14

Aliphatic Index 103.85

Aromaticity 0.1126

Extinction Coeff. Reduced 11920.00

Extinction Coeff. Oxidized 12045.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124799 VERIFIED: NO

Provenance & Taxonomy

OrganismJacana jacana (Wattled jacana) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria