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MYP_074241
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Basic Information
Cupiennin-1D (spiders, Arthropods, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
35 amino acids
C175H285N49O43S
Standard
Sequence
GFGSLFKFLAKKVAKTVAKQAAKQGAKYVANKHMQ
Physicochemical Analysis
3795.50 Da
10.54
7.84
7.57
0.2240
-0.27
0.69
-0.01
18.69
67.14
0.1143
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1522.61
-13.55
52.0
53.0
134.0
268.0
5.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0198636 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Cupiennin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis ATCC 29212
1.25-2.50 μM
MIC
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ371
RECORD: Rec_0199797 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Cupiennin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
0.31-0.63 μM
MIC
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ371
RECORD: Rec_0252570 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 77.1%, E 0.0%, T 11.4%, C 11.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0340659 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Cupiennin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
0.31-0.63 μM
MIC
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ371
RECORD: Rec_0352611 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis ATCC 29212
1.25-2.5 μM
MIC
PaperPubMed PMID: 11792701 | PubMed PMID: 10669026 PMID11792701;10669026 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11792701/
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