Peptide Database

Peptide NameCurvacin A / sakacin A

Function Ontology

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Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC181H268N48O55S3

DescriptionStandard

        YDNGIYCNNSKCWVNWGEAKENIAGIVISGWASGLAGM
    

Molecular Weight4092.55 Da

Isoelectric Point (pI)4.68

Net Charge (pH 7.0)-1.26

Net Charge (pH 7.4) -1.50

Charge Density (pH 7.0) -0.0331

GRAVY Index-0.04

Hydrophobic Moment 0.36

Boman Index0.22

Instability Index12.72

Aliphatic Index 77.11

Aromaticity 0.1316

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1667.93

LogP -16.76

H-bond Donors 59.0

H-bond Acceptors 57.0

Rotatable Bonds 131.0

Heavy Atoms 287.0

Ring Count 8.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141252 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterococcus faecium [Bacterium]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)