Peptide Database

Peptide NameBig gastrin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC168H241N41O53S

DescriptionStandard

        ELEPQGPPHLGTDLSKKQGPWAEEEAAYGWMDF
    

Molecular Weight3715.02 Da

Isoelectric Point (pI)4.25

Net Charge (pH 7.0)-5.07

Net Charge (pH 7.4) -5.30

Charge Density (pH 7.0) -0.1535

GRAVY Index-1.02

Hydrophobic Moment 0.39

Boman Index0.01

Instability Index52.18

Aliphatic Index 44.55

Aromaticity 0.1212

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1479.63

LogP -11.55

H-bond Donors 47.0

H-bond Acceptors 50.0

Rotatable Bonds 115.0

Heavy Atoms 263.0

Ring Count 11.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0077315 VERIFIED: YES

Provenance & Taxonomy

OrganismChinchilla chinchilla [Animal]

FamilyBig gastrin

Tax ID10152

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other Mods18:Pyrrolidone carboxylic acid; 28:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Myotropic

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour